Organic sulfuric acids and derivatives
Selleck Chemical LLC Sodium L-lactate
Sodium L-lactate is used as a food additive preservative acidity regulator and bulking agent
Medchemexpress LLC Bleomycin (sulfate) | 9041-93-4 | 99.49% | 1523 (average) | 100 MG
Bleomycin sulfate is a DNA synthesis inhibitor and an antitumor antibiotic. It acts as a DNA damaging agent, causing single and double strand breaks and single apurinic/apyrimidinic sites in DNA. This radiomimetic compound is used to induce pulmonary fibrosis models and is rapidly absorbed with high bioavailability.
- DNA synthesis inhibitor
- Antitumor antibiotic
- Radiomimetic compound, resembling the genetic effect of ionizing radiation
- Causes single and double strand breaks and single apurinic/apyrimidinic sites in DNA
- Can be used to induce pulmonary fibrosis models
- Rapidly absorbed after intramuscular, subcutaneous, intraperitoneal, or intrapleural administration
- Reaches peak plasma concentrations in approximately 60 minutes
- Less than 1% binds to plasma proteins
- High bioavailability
- Mean plasma clearance rate of about 70 mL/min/m2
Selleck Chemical LLC H-151
H-151 is a highly potent and covalent inhibitor of STING that has noteworthy inhibitory activity both in human cells and in vivo
TARGETMOL CHEMICALS INC ISAVUCONAZONIUM SULFATE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. Isavuconazole binds to and inhibits the fungal cytochrome P450 family enzyme lanosterol 14-alpha-demethylase (CYP51) which catalyzes the demethylation of lanosterol to yield ergosterol an important component of the fungal cell membrane. Isavuconazonium Sulfate is a prodrug of the triazole antifungal agent isavuconazole with broad-spectrum antifungal activity. Inhibition of CYP51 leads to a decrease in fungal ergosterol production and disrupts the synthesis of the fungal cell membrane which decreases membrane integrity increases cell membrane permeability and promotes the loss of essential intracellular elements. This results in fungal cell lysis and death. purity: 99%
Apexbio Technology LLC PLP (139-151) 122018-58-0 1mg
PLP 139-151 is a peptide derived from proteolipid protein (PLP) a major component of myelin in the central nervous system It is designed to trigger the proliferation and activation of CD4 T cells specific to myelin antigens thereby initiating autoimmune responses against neural tissues PLP 139-151 exerts its biological activity primarily through the induction of T cell-mediated immune responses In experimental autoimmune encephalomyelitis (EAE) models PLP 139-151 demonstrates immunodominant activity by facilitating disease induction Based on these pharmacological properties PLP 139-151 holds research potential in studies of T cell-mediated immune events autoimmune inflammation and the evaluation of therapeutic strategies targeting immune modulation and tolerance induction in neuroimmunological diseases
Apexbio Technology LLC Cystamine 51-85-4 50mg
Cystamine (CAS 51-85-4) is a disulfide derivative of cysteamine that functions as an inhibitor of transglutaminase (Tgase) activity Additionally Cystamine has been shown to suppress caspase-3 activity in vitro with a reported IC50 of approximately 23 6 M Due to its ability to modulate these enzymatic pathways Cystamine is commonly utilized in studies of neurodegenerative conditions such as Huntington s disease where it is employed to investigate neuroprotective mechanisms and to evaluate potential therapeutic effects in disease models
Selleck Chemical LLC Vincristine sulfate S1241-10mM/1mL
Vincristine sulfate is an inhibitor of polymerization of microtubules by binding to tubulin with IC50 of 32 M in a cell-free assay Vincristine sulfate induces apoptosis
Selleck Chemical LLC Minoxidil sulphate S5228-1g
Minoxidil (U-58838) is a potent direct-acting peripheral vasodilator that reduces peripheral resistance and produces a fall in blood pressure
Medchemexpress LLC Heparan sulfate | 9050-30-0 | 593.47 (monomer) | C12H19NO20S3 (monomer) | 25 MG
Heparan sulfate is a complex, linear glycosaminoglycan used in biochemical and cell biology research to probe growth factor binding, cell signaling, and extracellular matrix interactions. Supplied as a dry material with reported monomer parameters for reference, it dissolves in aqueous buffers for use in assays and cell studies.
- Supports study of growth factor signaling, including FGFR and Wnt pathways.
- Suitable for extracellular matrix and proteoglycan research.
- Soluble in water and PBS; ultrasonic agitation may be required for complete dissolution.
- Monomer molecular formula C12H19NO20S3 and monomer molecular weight 593.47 for reference.
- Storage guidance available for sealed material and solutions to preserve stability.
Medchemexpress LLC Sodium laureth sulfate | 9004-82-4 | 70.3% | (C2H4O)nC12H26O4S.Na | 50 G
Sodium laureth sulfate (70% in water) is an anionic active agent that possesses excellent decontamination, emulsification, dispersion, wetting, antifungal, and other properties.
- Has excellent decontamination properties
- Provides emulsification
- Offers dispersion
- Aids in wetting
- Exhibits antifungal properties
Medchemexpress LLC Sodium laureth sulfate | 9004-82-4 | 70% | (C2H4O)nC12H26O4S.Na | 100 G
Sodium laureth sulfate (70% in water) is an anionic active agent known for its excellent decontamination, emulsification, dispersion, wetting, and antifungal properties. This product is intended for research use only and is not sold to patients.
- Possesses excellent decontamination properties
- Offers emulsification and dispersion capabilities
- Provides effective wetting and antifungal action
- Enhances inactivation efficiency against S. cerevisiae cells when combined with plasma-activated water
- Disrupts membrane integrity and increases cell membrane permeability in S. cerevisiae cells
- Generates reactive oxygen species (ROS) in S. cerevisiae cells
- Elevates activities of various lysosomal enzymes in animal models
Selleck Chemical LLC H-151
H-151 is a highly potent and covalent inhibitor of STING that has noteworthy inhibitory activity both in human cells and in vivo
Sigma Aldrich Fine Chemicals Biosciences Polymyxin B sulfate salt p
Polymyxin B is a member of the polymyxin group of antibiotics obtained from different strains of Bacillus polymyxa and related species. It contains a cyclic heptapeptide unit and a tripeptide side chain which is N-acylated by a fatty acyl residue. Polymyxin B sulfate salt is generally used for the treatment of Gram-negative bacterial infections.Chemical structure peptide
Sigma Aldrich Fine Chemicals Biosciences Sodium azide BioUltra 99.55G
SODIUM Sodium azide BioUltra 99.55G